› 7smc

X-ray diffraction
2.7Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151278 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Retinoblastoma-like protein 1 Chains: A, C
Molecule details ›
Chains: A, C
Length: 371 amino acids
Theoretical weight: 43.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P28749 (Residues: 391-972; Coverage: 35%)
Gene name: RBL1
Sequence domains:
AT-rich interactive domain-containing protein 4A Chains: B, D
Molecule details ›
Chains: B, D
Length: 15 amino acids
Theoretical weight: 1.66 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P29374 (Residues: 953-967; Coverage: 1%)
Gene names: ARID4A, RBBP1, RBP1

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P1
Unit cell:
a: 62.863Å b: 62.923Å c: 71.274Å
α: 69.89° β: 76° γ: 74.36°
R-values:
R R work R free
0.241 0.238 0.298
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

1 review citation

Vital for Viruses: Intrinsically Disordered Proteins.
Dyson HJ. (2023)
1 other article

1 mention without citation

Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family.
Putta et al. (2022)