Function and Biology Details
Reaction catalysed:
ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126269 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Eukaryotic elongation factor 2 kinase
Molecule details ›
Chain: A
Length: 531 amino acids
Theoretical weight: 60.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Alpha-kinase family
Length: 531 amino acids
Theoretical weight: 60.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O00418 (Residues: 70-358, 490-725; Coverage: 72%)
Sequence domains: Alpha-kinase family
Calmodulin-1
Molecule details ›
Chain: B
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: EF-hand domain pair
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P0DP23 (Residues: 2-149; Coverage: 99%)
Sequence domains: EF-hand domain pair
