› 7seg

X-ray diffraction
2.16Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-209378 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
anti-CD16a Fab light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 236 amino acids
Theoretical weight: 25.66 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
anti-CD16A Fab heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 247 amino acids
Theoretical weight: 26.65 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Low affinity immunoglobulin gamma Fc region receptor III-A Chains: C, D
Molecule details ›
Chains: C, D
Length: 180 amino acids
Theoretical weight: 20.46 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P08637 (Residues: 16-193; Coverage: 74%)
Gene names: CD16A, FCG3, FCGR3, FCGR3A, IGFR3
Sequence domains: Immunoglobulin domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Ligand NAG 2 x NAG
2 bound ligands:
Ligand GOL 1 x GOL
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21
Unit cell:
a: 45.307Å b: 220.56Å c: 70.825Å
α: 90° β: 108.55° γ: 90°
R-values:
R R work R free
0.194 0.189 0.234
Expression systems:
  • Homo sapiens
  • Spodoptera frugiperda

Quick links

Citations

7 review citations

NK cells are never alone: crosstalk and communication in tumour microenvironments.
Zhou et al. (2023)
6 more