› 7r85

X-ray diffraction
1.45Å resolution

Structure of mouse Bai1 (ADGRB1) TSR3 domain

Released:
DOI: 10.2210/pdb7r85/pdb
PDB entry 7r85 coloured by chain, front view.
PDB entry 7r85 coloured by chain, side view.
PDB entry 7r85 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Wang J, Miao Y, Wicklein R, Sun Z, Wang J, Jude KM, Fernandes RA, Merrill SA, Wernig M, Garcia KC, Südhof TC
Cell 184 5869-5885.e25 (2021)
PMID: 34758294

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174842 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Vasculostatin-120 Chain: A
Molecule details ›
Chain: A
Length: 54 amino acids
Theoretical weight: 6.08 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q3UHD1 (Residues: 409-462; Coverage: 4%)
Gene names: Adgrb1, Bai1
Sequence domains: Thrombospondin type 1 domain

Ligands and Environments

Carbohydrate polymer : NEW Components: FUC, BGC
Ligand FUC 1 x FUC
Ligand BGC 1 x BGC
1 bound ligand:
Ligand MAN 2 x MAN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P4222
Unit cell:
a: 43.915Å b: 43.915Å c: 64.312Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.178 0.211
Expression system: Homo sapiens

Quick links

Citations

6 review citations

Protein posttranslational modifications in health and diseases: Functions, regulatory mechanisms, and therapeutic implications.
Zhong et al. (2023)
5 more

1 mention without citation

RTN4/NoGo-receptor binding to BAI adhesion-GPCRs regulates neuronal development.
Wang et al. (2021)