› 7qvp

Electron Microscopy
3Å resolution

Human collided disome (di-ribosome) stalled on XBP1 mRNA

Released:
DOI: 10.2210/pdb7qvp/pdb
PDB entry 7qvp coloured by chain, front view.
PDB entry 7qvp coloured by chain, side view.
PDB entry 7qvp coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
Narita M, Denk T, Matsuo Y, Sugiyama T, Kikuguchi C, Ito S, Sato N, Suzuki T, Hashimoto S, Machová I, Tesina P, Beckmann R, Inada T
Nat Commun 13 6411 (2022)
PMID: 36302773
Related structures: EMD-14181

Function and Biology Details

Reaction catalysed: 
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 162-mer (preferred)
PDBe Complex ID:
PDB-CPX-103212 (preferred)
Entry contents:
76 distinct polypeptide molecules
9 distinct RNA molecules
Macromolecules (85 distinct):
Large ribosomal subunit protein uL2 Chains: LA, MA
Molecule details ›
Chains: LA, MA
Length: 257 amino acids
Theoretical weight: 28.09 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A8B8VPA8 (Residues: 1-257; Coverage: 100%)
Gene name: RPL8
Sequence domains:
Large ribosomal subunit protein uL3 Chains: LB, MB
Molecule details ›
Chains: LB, MB
Length: 403 amino acids
Theoretical weight: 46.21 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P39023 (Residues: 1-403; Coverage: 100%)
Gene names: OK/SW-cl.32, RPL3
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4 Chains: LC, MC
Molecule details ›
Chains: LC, MC
Length: 427 amino acids
Theoretical weight: 47.8 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P36578 (Residues: 1-427; Coverage: 100%)
Gene names: RPL1, RPL4
Sequence domains:
Large ribosomal subunit protein uL18 Chains: LD, MD
Molecule details ›
Chains: LD, MD
Length: 297 amino acids
Theoretical weight: 34.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46777 (Residues: 1-297; Coverage: 100%)
Gene names: MSTP030, RPL5
Sequence domains:
Large ribosomal subunit protein eL6 Chains: LE, ME
Molecule details ›
Chains: LE, ME
Length: 288 amino acids
Theoretical weight: 32.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q02878 (Residues: 1-288; Coverage: 100%)
Gene names: RPL6, TXREB1
Sequence domains:
Large ribosomal subunit protein uL30 Chains: LF, MF
Molecule details ›
Chains: LF, MF
Length: 248 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P18124 (Residues: 1-248; Coverage: 100%)
Gene name: RPL7
Sequence domains:
Large ribosomal subunit protein eL8 Chains: LG, MG
Molecule details ›
Chains: LG, MG
Length: 266 amino acids
Theoretical weight: 30.06 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62424 (Residues: 1-266; Coverage: 100%)
Gene names: RPL7A, SURF-3, SURF3
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL6 Chains: LH, MH
Molecule details ›
Chains: LH, MH
Length: 192 amino acids
Theoretical weight: 21.9 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P32969 (Residues: 1-192; Coverage: 100%)
Gene names: OK/SW-cl.103, RPL9, RPL9P7, RPL9P8, RPL9P9
Sequence domains: Ribosomal protein L6
Ribosomal protein uL16-like Chains: LI, MI
Molecule details ›
Chains: LI, MI
Length: 214 amino acids
Theoretical weight: 24.57 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96L21 (Residues: 1-214; Coverage: 100%)
Gene name: RPL10L
Sequence domains: Ribosomal protein L16p/L10e
Large ribosomal subunit protein uL5 Chains: LJ, MJ
Molecule details ›
Chains: LJ, MJ
Length: 178 amino acids
Theoretical weight: 20.29 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62913 (Residues: 1-178; Coverage: 100%)
Gene name: RPL11
Sequence domains:
Large ribosomal subunit protein eL13 Chains: LL, ML
Molecule details ›
Chains: LL, ML
Length: 211 amino acids
Theoretical weight: 24.32 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P26373 (Residues: 1-211; Coverage: 100%)
Gene names: BBC1, OK/SW-cl.46, RPL13
Sequence domains: Ribosomal protein L13e
Large ribosomal subunit protein eL14 Chains: LM, MM
Molecule details ›
Chains: LM, MM
Length: 215 amino acids
Theoretical weight: 23.49 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P50914 (Residues: 1-215; Coverage: 100%)
Gene name: RPL14
Sequence domains: Ribosomal protein L14
Ribosomal protein L15 Chains: LN, MN
Molecule details ›
Chains: LN, MN
Length: 204 amino acids
Theoretical weight: 24.21 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: L8Y0W1 (Residues: 1-204; Coverage: 100%)
Gene names: TREES_T100017479, TREES_T100017480
Sequence domains: Ribosomal L15
Large ribosomal subunit protein uL13 Chains: LO, MO
Molecule details ›
Chains: LO, MO
Length: 203 amino acids
Theoretical weight: 23.63 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P40429 (Residues: 1-203; Coverage: 100%)
Gene name: RPL13A
Sequence domains: Ribosomal protein L13
Large ribosomal subunit protein uL22 Chain: LP
Molecule details ›
Chain: LP
Length: 154 amino acids
Theoretical weight: 17.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P18621 (Residues: 1-154; Coverage: 84%)
Gene name: RPL17
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein eL18 Chains: LQ, MQ
Molecule details ›
Chains: LQ, MQ
Length: 188 amino acids
Theoretical weight: 21.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q07020 (Residues: 1-188; Coverage: 100%)
Gene name: RPL18
Sequence domains: Ribosomal protein 60S L18 and 50S L18e
Ribosomal protein L19 Chains: LR, MR
Molecule details ›
Chains: LR, MR
Length: 196 amino acids
Theoretical weight: 23.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A2J8KH59 (Residues: 1-196; Coverage: 100%)
Gene name: CK820_G0039174
Sequence domains: Ribosomal protein L19e
Large ribosomal subunit protein eL20 Chains: LS, MS
Molecule details ›
Chains: LS, MS
Length: 176 amino acids
Theoretical weight: 20.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q02543 (Residues: 1-176; Coverage: 100%)
Gene name: RPL18A
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Large ribosomal subunit protein eL21 Chains: LT, MT
Molecule details ›
Chains: LT, MT
Length: 160 amino acids
Theoretical weight: 18.61 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46778 (Residues: 1-160; Coverage: 100%)
Gene name: RPL21
Sequence domains: Ribosomal protein L21e
Large ribosomal subunit protein eL22 Chains: LU, MU
Molecule details ›
Chains: LU, MU
Length: 128 amino acids
Theoretical weight: 14.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P35268 (Residues: 1-128; Coverage: 100%)
Gene name: RPL22
Sequence domains: Ribosomal L22e protein family
Large ribosomal subunit protein uL14 Chains: LV, MV
Molecule details ›
Chains: LV, MV
Length: 140 amino acids
Theoretical weight: 14.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A3P9HH38 (Residues: 1-140; Coverage: 100%)
Sequence domains: Ribosomal protein L14p/L23e
Large ribosomal subunit protein eL24 Chains: LW, MW
Molecule details ›
Chains: LW, MW
Length: 157 amino acids
Theoretical weight: 17.83 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: F2X267 (Residues: 1-157; Coverage: 100%)
Gene names: LOC117798870, RPL24, Rpl24
Sequence domains: Ribosomal protein L24e
Large ribosomal subunit protein uL23 Chains: LX, MX
Molecule details ›
Chains: LX, MX
Length: 156 amino acids
Theoretical weight: 17.74 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62750 (Residues: 1-156; Coverage: 100%)
Gene name: RPL23A
Sequence domains:
Large ribosomal subunit protein uL24 Chains: LY, MY
Molecule details ›
Chains: LY, MY
Length: 145 amino acids
Theoretical weight: 17.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A5N3X333 (Residues: 1-145; Coverage: 100%)
Gene name: FD755_020861
Sequence domains:
60S ribosomal protein L27 Chains: LZ, MZ
Molecule details ›
Chains: LZ, MZ
Length: 136 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A851LWS6 (Residues: 1-136; Coverage: 100%)
Gene names: CORCRI_R11721, Rpl27
Sequence domains:
Large ribosomal subunit protein uL15 Chains: La, Ma
Molecule details ›
Chains: La, Ma
Length: 148 amino acids
Theoretical weight: 16.6 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46776 (Residues: 1-148; Coverage: 100%)
Gene name: RPL27A
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
Large ribosomal subunit protein eL29 Chains: Lb, Mb
Molecule details ›
Chains: Lb, Mb
Length: 159 amino acids
Theoretical weight: 17.8 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P47914 (Residues: 1-159; Coverage: 100%)
Gene name: RPL29
Sequence domains: Ribosomal L29e protein family
Large ribosomal subunit protein eL30 Chains: Lc, Mc
Molecule details ›
Chains: Lc, Mc
Length: 115 amino acids
Theoretical weight: 12.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62888 (Residues: 1-115; Coverage: 100%)
Gene name: RPL30
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein eL31 Chains: Ld, Md
Molecule details ›
Chains: Ld, Md
Length: 125 amino acids
Theoretical weight: 14.49 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: G7NZE1 (Residues: 1-125; Coverage: 100%)
Sequence domains: Ribosomal protein L31e
Large ribosomal subunit protein eL32 Chains: Le, Me
Molecule details ›
Chains: Le, Me
Length: 135 amino acids
Theoretical weight: 15.9 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62910 (Residues: 1-135; Coverage: 100%)
Gene names: PP9932, RPL32
Sequence domains: Ribosomal protein L32
Large ribosomal subunit protein eL33 Chains: Lf, Mf
Molecule details ›
Chains: Lf, Mf
Length: 110 amino acids
Theoretical weight: 12.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P18077 (Residues: 1-110; Coverage: 100%)
Gene names: GIG33, RPL35A
Sequence domains: Ribosomal protein L35Ae
Large ribosomal subunit protein eL34 Chains: Lg, Mg
Molecule details ›
Chains: Lg, Mg
Length: 117 amino acids
Theoretical weight: 13.33 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A1U7T3M5 (Residues: 1-117; Coverage: 100%)
Gene name: RPL34
Sequence domains: Ribosomal protein L34e
Large ribosomal subunit protein uL29 Chains: Lh, Mh
Molecule details ›
Chains: Lh, Mh
Length: 123 amino acids
Theoretical weight: 14.59 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P42766 (Residues: 1-123; Coverage: 100%)
Gene name: RPL35
Sequence domains: Ribosomal L29 protein
Large ribosomal subunit protein eL36 Chains: Li, Mi
Molecule details ›
Chains: Li, Mi
Length: 105 amino acids
Theoretical weight: 12.29 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3U8 (Residues: 1-105; Coverage: 100%)
Gene name: RPL36
Sequence domains: Ribosomal protein L36e
Ribosomal protein L37 Chains: Lj, Mj
Molecule details ›
Chains: Lj, Mj
Length: 88 amino acids
Theoretical weight: 10.38 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A2Y9RW09 (Residues: 1-88; Coverage: 91%)
Gene names: LOC101347038, RPL37
Sequence domains: Ribosomal protein L37e
Large ribosomal subunit protein eL38 Chains: Lk, Mk
Molecule details ›
Chains: Lk, Mk
Length: 70 amino acids
Theoretical weight: 8.24 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A1A7W9T9 (Residues: 1-70; Coverage: 100%)
Gene name: RPL38
Sequence domains: Ribosomal L38e protein family
Large ribosomal subunit protein eL39 Chains: Ll, Ml
Molecule details ›
Chains: Ll, Ml
Length: 51 amino acids
Theoretical weight: 6.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A7N4PFJ2 (Residues: 1-51; Coverage: 100%)
Gene name: LOC100920732
Sequence domains: Ribosomal L39 protein
Ubiquitin-ribosomal protein eL40 fusion protein Chains: Lm, Mm
Molecule details ›
Chains: Lm, Mm
Length: 128 amino acids
Theoretical weight: 14.76 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A8C8Y9V5 (Residues: 1-128; Coverage: 100%)
Gene name: UBA52
Sequence domains:
Small ribosomal subunit protein eS32 Chains: Ln, Mn
Molecule details ›
Chains: Ln, Mn
Length: 25 amino acids
Theoretical weight: 3.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62945 (Residues: 1-25; Coverage: 100%)
Gene name: RPL41
Sequence domains: Ribosomal protein L41
Large ribosomal subunit protein eL42 Chains: Lo, Mo
Molecule details ›
Chains: Lo, Mo
Length: 106 amino acids
Theoretical weight: 12.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: J3KQN4 (Residues: 37-142; Coverage: 75%)
Gene name: RPL36A
Sequence domains: Ribosomal protein L44
60S ribosomal protein L37a Chains: Lp, Mp
Molecule details ›
Chains: Lp, Mp
Length: 92 amino acids
Theoretical weight: 10.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A6I9ZMF9 (Residues: 1-92; Coverage: 100%)
Gene name: RPL37A
Sequence domains: Ribosomal L37ae protein family
Large ribosomal subunit protein eL28 Chains: Lr, Mr
Molecule details ›
Chains: Lr, Mr
Length: 137 amino acids
Theoretical weight: 15.78 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46779 (Residues: 1-137; Coverage: 100%)
Gene name: RPL28
Sequence domains: Ribosomal L28e protein family
Large ribosomal subunit protein uL22 Chain: MP
Molecule details ›
Chain: MP
Length: 184 amino acids
Theoretical weight: 21.44 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P18621 (Residues: 1-184; Coverage: 100%)
Gene name: RPL17
Sequence domains: Ribosomal protein L22p/L17e
Small ribosomal subunit protein uS2 Chains: RA, SA
Molecule details ›
Chains: RA, SA
Length: 295 amino acids
Theoretical weight: 32.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08865 (Residues: 1-295; Coverage: 100%)
Gene names: LAMBR, LAMR1, RPSA
Sequence domains:
Small ribosomal subunit protein eS1 Chains: RB, SB
Molecule details ›
Chains: RB, SB
Length: 264 amino acids
Theoretical weight: 30 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P61247 (Residues: 1-264; Coverage: 100%)
Gene names: FTE1, MFTL, RPS3A
Sequence domains: Ribosomal S3Ae family
Small ribosomal subunit protein uS5 Chains: RC, SC
Molecule details ›
Chains: RC, SC
Length: 293 amino acids
Theoretical weight: 31.38 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P15880 (Residues: 1-293; Coverage: 100%)
Gene names: RPS2, RPS4
Sequence domains:
Small ribosomal subunit protein uS3 Chains: RD, SD
Molecule details ›
Chains: RD, SD
Length: 243 amino acids
Theoretical weight: 26.73 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P23396 (Residues: 1-243; Coverage: 100%)
Gene names: OK/SW-cl.26, RPS3
Sequence domains:
Small ribosomal subunit protein eS4, X isoform Chains: RE, SE
Molecule details ›
Chains: RE, SE
Length: 263 amino acids
Theoretical weight: 29.65 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62701 (Residues: 1-263; Coverage: 100%)
Gene names: CCG2, RPS4, RPS4X, SCAR
Sequence domains:
Small ribosomal subunit protein uS7 Chains: RF, SF
Molecule details ›
Chains: RF, SF
Length: 204 amino acids
Theoretical weight: 22.91 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A6J0Y1Z7 (Residues: 1-204; Coverage: 100%)
Gene name: RPS5
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein eS6 Chains: RG, SG
Molecule details ›
Chains: RG, SG
Length: 249 amino acids
Theoretical weight: 28.75 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62753 (Residues: 1-249; Coverage: 100%)
Gene names: OK/SW-cl.2, RPS6
Sequence domains: Ribosomal protein S6e
Small ribosomal subunit protein eS7 Chains: RH, SH
Molecule details ›
Chains: RH, SH
Length: 194 amino acids
Theoretical weight: 22.17 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62082 (Residues: 1-194; Coverage: 100%)
Gene name: Rps7
Sequence domains: Ribosomal protein S7e
Small ribosomal subunit protein eS8 Chains: RI, SI
Molecule details ›
Chains: RI, SI
Length: 208 amino acids
Theoretical weight: 24.26 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62241 (Residues: 1-208; Coverage: 100%)
Gene names: OK/SW-cl.83, RPS8
Sequence domains: Ribosomal protein S8e
Small ribosomal subunit protein uS4 Chains: RJ, SJ
Molecule details ›
Chains: RJ, SJ
Length: 194 amino acids
Theoretical weight: 22.64 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A6J0B498 (Residues: 1-194; Coverage: 100%)
Gene name: RPS9
Sequence domains:
Small ribosomal subunit protein eS10 Chains: RK, SK
Molecule details ›
Chains: RK, SK
Length: 165 amino acids
Theoretical weight: 18.93 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46783 (Residues: 1-165; Coverage: 100%)
Gene name: RPS10
Sequence domains: Plectin/S10 domain
Small ribosomal subunit protein uS17 Chains: RL, SL
Molecule details ›
Chains: RL, SL
Length: 158 amino acids
Theoretical weight: 18.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A8B8VW69 (Residues: 1-158; Coverage: 100%)
Gene name: RPS11
Sequence domains:
Small ribosomal subunit protein uS15 Chains: RN, SN
Molecule details ›
Chains: RN, SN
Length: 151 amino acids
Theoretical weight: 17.26 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A663F1C0 (Residues: 1-151; Coverage: 100%)
Gene name: RPS13
Sequence domains:
Small ribosomal subunit protein uS11 Chains: RO, SO
Molecule details ›
Chains: RO, SO
Length: 151 amino acids
Theoretical weight: 16.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A7L0BEC6 (Residues: 1-151; Coverage: 100%)
Gene names: Rps14, SPITYR_R00187
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS19 Chains: RP, SP
Molecule details ›
Chains: RP, SP
Length: 145 amino acids
Theoretical weight: 17.08 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A2K6QL61 (Residues: 1-145; Coverage: 100%)
Sequence domains: Ribosomal protein S19
40S ribosomal protein S16 Chains: RQ, SQ
Molecule details ›
Chains: RQ, SQ
Length: 146 amino acids
Theoretical weight: 16.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A4W2HV66 (Residues: 1-146; Coverage: 100%)
Gene name: RPS16
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein eS17 Chains: RR, SR
Molecule details ›
Chains: RR, SR
Length: 135 amino acids
Theoretical weight: 15.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08708 (Residues: 1-135; Coverage: 100%)
Gene names: RPS17, RPS17L
Sequence domains: Ribosomal S17
Small ribosomal subunit protein uS13 Chains: RS, SS
Molecule details ›
Chains: RS, SS
Length: 152 amino acids
Theoretical weight: 17.76 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: H0WTR0 (Residues: 1-152; Coverage: 100%)
Gene name: RPS18
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein eS19 Chains: RT, ST
Molecule details ›
Chains: RT, ST
Length: 145 amino acids
Theoretical weight: 16.09 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A2Y9E7Q1 (Residues: 1-145; Coverage: 100%)
Gene name: RPS19
Sequence domains: Ribosomal protein S19e
Small ribosomal subunit protein uS10 Chains: RU, SU
Molecule details ›
Chains: RU, SU
Length: 119 amino acids
Theoretical weight: 13.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P60868 (Residues: 1-119; Coverage: 100%)
Gene name: Rps20
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein eS21 Chains: RV, SV
Molecule details ›
Chains: RV, SV
Length: 83 amino acids
Theoretical weight: 9.12 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P63220 (Residues: 1-83; Coverage: 100%)
Gene name: RPS21
Sequence domains: Ribosomal protein S21e
Small ribosomal subunit protein uS8 Chains: RW, SW
Molecule details ›
Chains: RW, SW
Length: 130 amino acids
Theoretical weight: 14.87 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A2K5QKS6 (Residues: 1-130; Coverage: 100%)
Sequence domains: Ribosomal protein S8
Small ribosomal subunit protein uS12 Chains: RX, SX
Molecule details ›
Chains: RX, SX
Length: 143 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A340WVW7 (Residues: 1-143; Coverage: 100%)
Gene name: RPS23
Sequence domains: Ribosomal protein S12/S23
Small ribosomal subunit protein eS24 Chains: RY, SY
Molecule details ›
Chains: RY, SY
Length: 133 amino acids
Theoretical weight: 15.46 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62847 (Residues: 1-133; Coverage: 100%)
Gene name: RPS24
Sequence domains: Ribosomal protein S24e
40S ribosomal protein S25 Chains: RZ, SZ
Molecule details ›
Chains: RZ, SZ
Length: 125 amino acids
Theoretical weight: 13.78 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A6J3IG71 (Residues: 1-125; Coverage: 100%)
Gene names: LOC116557045, RPS25
Sequence domains: S25 ribosomal protein
40S ribosomal protein S26 Chains: Ra, Sa
Molecule details ›
Chains: Ra, Sa
Length: 101 amino acids
Theoretical weight: 11.62 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A6J2NCX2 (Residues: 1-101; Coverage: 88%)
Gene names: HJG60_016628, RPS26
Sequence domains: Ribosomal protein S26e
40S ribosomal protein S27 Chains: Rb, Sb
Molecule details ›
Chains: Rb, Sb
Length: 84 amino acids
Theoretical weight: 9.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A7J8BG50 (Residues: 1-84; Coverage: 100%)
Gene name: HJG63_016964
Sequence domains: Ribosomal protein S27
Small ribosomal subunit protein eS28 Chains: Rc, Sc
Molecule details ›
Chains: Rc, Sc
Length: 69 amino acids
Theoretical weight: 7.86 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A3M0JHZ8 (Residues: 1-69; Coverage: 100%)
Gene name: DUI87_22462
Sequence domains: Ribosomal protein S28e
Small ribosomal subunit protein uS14 Chains: Rd, Sd
Molecule details ›
Chains: Rd, Sd
Length: 56 amino acids
Theoretical weight: 6.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A2J8WKD7 (Residues: 1-56; Coverage: 100%)
Gene name: CR201_G0009512
Sequence domains: Ribosomal protein S14p/S29e
Ubiquitin-like domain-containing protein Chains: Re, Se
Molecule details ›
Chains: Re, Se
Length: 59 amino acids
Theoretical weight: 6.67 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A2K6U587 (Residues: 75-133; Coverage: 44%)
Sequence domains: Ribosomal protein S30
40S ribosomal protein S12 Chain: Rf
Molecule details ›
Chain: Rf
Length: 132 amino acids
Theoretical weight: 14.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A671DUR2 (Residues: 1-132; Coverage: 100%)
Gene name: mRhiFer1_014634
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Small ribosomal subunit protein RACK1 Chains: Rg, Sg
Molecule details ›
Chains: Rg, Sg
Length: 317 amino acids
Theoretical weight: 35.12 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A2K6K8B0 (Residues: 1-317; Coverage: 100%)
Gene name: RACK1
Sequence domains: WD domain, G-beta repeat
Ubiquitin-ribosomal protein eS31 fusion protein Chain: Rh
Molecule details ›
Chain: Rh
Length: 156 amino acids
Theoretical weight: 18 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: A0A8C0T835 (Residues: 1-156; Coverage: 100%)
Gene name: RPS27A
Sequence domains:
Messenger RNA Chain: A4
Molecule details ›
Chain: A4
Length: 14 nucleotides
Theoretical weight: 4.24 KDa
Messenger RNA Chain: A5
Molecule details ›
Chain: A5
Length: 11 nucleotides
Theoretical weight: 3.32 KDa
tRNA P/P Chains: B4, D5
Molecule details ›
Chains: B4, D5
Length: 76 nucleotides
Theoretical weight: 24.49 KDa
Sequence domains: tRNA
tRNA P/E Chain: B5
Molecule details ›
Chain: B5
Length: 75 nucleotides
Theoretical weight: 24.23 KDa
Sequence domains: tRNA
tNRA E/E Chain: CC
Molecule details ›
Chain: CC
Length: 75 nucleotides
Theoretical weight: 24 KDa
Sequence domains: tRNA
5.8S ribosomal RNA Chains: L1, L8
Molecule details ›
Chains: L1, L8
Length: 157 nucleotides
Theoretical weight: 50.45 KDa
Sequence domains: 5.8S ribosomal RNA
28S ribosomal RNA Chains: L5, L6
Molecule details ›
Chains: L5, L6
Length: 5227 nucleotides
Theoretical weight: 1690.72 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA Chains: L7, L9
Molecule details ›
Chains: L7, L9
Length: 121 nucleotides
Theoretical weight: 39 KDa
Sequence domains: 5S ribosomal RNA
18S Ribosomal RNA Chains: S2, S3
Molecule details ›
Chains: S2, S3
Length: 1869 nucleotides
Theoretical weight: 602.78 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3Å
Relevant EMDB volumes: EMD-14181

Quick links

Citations

2 review citations

Pleiotropic Roles of a KEAP1-Associated Deubiquitinase, OTUD1.
Oikawa et al. (2023)
1 more