7ott

Electron Microscopy
3.84Å resolution

Metabolon-embedded pyruvate dehydrogenase complex E2 core at near-atomic resolution

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine
Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo 60-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 459 amino acids
Theoretical weight: 48.78 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
UniProt:
  • Canonical: G0S4X6 (Residues: 1-459; Coverage: 100%)
Gene name: CTHT_0032020
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.84Å
Relevant EMDB volumes: EMD-13066