› 6zwt

X-ray diffraction
2.2Å resolution

Crystal structure of DNA-binding domain of OmpR of two-component system of Acinetobacter baumannii

Released:
DOI: 10.2210/pdb6zwt/pdb
PDB 6zwt coloured by chain and viewed from the front.
PDB 6zwt coloured by chain and viewed from the side.
PDB 6zwt coloured by chain and viewed from the top.
Source organism: Acinetobacter baumannii SDF
Primary publication:
Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis.
Trebosc V, Lucchini V, Narwal M, Wicki B, Gartenmann S, Schellhorn B, Schill J, Bourotte M, Frey D, Grünberg J, Trauner A, Ferrari L, Felici A, Champion OL, Gitzinger M, Lociuro S, Kammerer RA, Kemmer C, Pieren M
Virulence 13 1868-1883 (2022)
PMID: 36261919

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Two-component response regulator Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 114 amino acids
Theoretical weight: 13.11 KDa
Source organism: Acinetobacter baumannii SDF
Expression system: Escherichia coli
UniProt:
  • Canonical: B0VPC9 (Residues: 148-254; Coverage: 42%)
Gene names: ABSDF0250, ompR
Sequence domains: Transcriptional regulatory protein, C terminal

Ligands and Environments

3 bound ligands:
Ligand SO4 3 x SO4
Ligand PEG 1 x PEG
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P1
Unit cell:
a: 48.47Å b: 49.703Å c: 52.727Å
α: 90.07° β: 99.01° γ: 103.98°
R-values:
R R work R free
0.243 0.242 0.273
Expression system: Escherichia coli

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