6zvq

X-ray diffraction
2.03Å resolution

Complex between SMAD2 MH2 domain and peptide from Ski corepressor

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-146310 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Mothers against decapentaplegic homolog 2 Chain: A
Molecule details ›
Chain: A
Length: 227 amino acids
Theoretical weight: 25.54 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q15796 (Residues: 241-467; Coverage: 49%)
Gene names: MADH2, MADR2, SMAD2
Sequence domains: MH2 domain
Ski oncogene Chain: B
Molecule details ›
Chain: B
Length: 35 amino acids
Theoretical weight: 3.85 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P12755 (Residues: 11-45; Coverage: 5%)
Gene name: SKI

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: I213
Unit cell:
a: 113.82Å b: 113.82Å c: 113.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.164 0.21
Expression systems:
  • Spodoptera frugiperda
  • Not provided