6zn8

X-ray diffraction
3.21Å resolution

Crystal structure of the H. influenzae VapXD toxin-antitoxin complex

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-175728 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Endoribonuclease VapD Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 100 amino acids
Theoretical weight: 11.92 KDa
Source organism: Haemophilus influenzae 86-028NP
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4QN95 (Residues: 1-92; Coverage: 100%)
Gene names: NTHI0577, vapD
VapX Chains: C, F
Molecule details ›
Chains: C, F
Length: 81 amino acids
Theoretical weight: 9.09 KDa
Source organism: Haemophilus influenzae 86-028NP
Expression system: Escherichia coli
UniProt:
  • Canonical: Q4QN94 (Residues: 2-63; Coverage: 98%)
Gene names: NTHI0578, vapX
Sequence domains: Family of unknown function (DUF5397)

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: I4132
Unit cell:
a: 256.75Å b: 256.75Å c: 256.75Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.262 0.258 0.299
Expression system: Escherichia coli