› 6zm6

Electron Microscopy
2.59Å resolution

Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA

Released:
DOI: 10.2210/pdb6zm6/pdb
PDB 6zm6 coloured by chain and viewed from the front.
PDB 6zm6 coloured by chain and viewed from the side.
PDB 6zm6 coloured by chain and viewed from the top.
Source organism: Homo sapiens
Primary publication:
Mechanism of membrane-tethered mitochondrial protein synthesis
Itoh Y, Andrell J, Choi A, Richter U, Maiti P, Barrientos A, Battersby BJ, Amunts A
Science (2021)
Related structures: EMD-11279

Function and Biology Details

Reaction catalysed: 
N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 92-mer (preferred)
Entry contents:
81 distinct polypeptide molecules
6 distinct RNA molecules
Macromolecules (87 distinct):
39S ribosomal protein L2, mitochondrial Chain: D
Molecule details ›
Chain: D
Length: 305 amino acids
Theoretical weight: 33.36 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q5T653 (Residues: 1-305; Coverage: 100%)
Gene names: CGI-22, MRPL2
Sequence domains:
39S ribosomal protein L3, mitochondrial Chain: E
Molecule details ›
Chain: E
Length: 348 amino acids
Theoretical weight: 38.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P09001 (Residues: 1-348; Coverage: 100%)
Gene names: MRL3, MRPL3, RPML3
Sequence domains: Ribosomal protein L3
39S ribosomal protein L4, mitochondrial Chain: F
Molecule details ›
Chain: F
Length: 311 amino acids
Theoretical weight: 34.97 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYD3 (Residues: 1-311; Coverage: 100%)
Gene names: CDABP0091, CGI-28, MRPL4
Sequence domains: Ribosomal protein L4/L1 family
39S ribosomal protein L9, mitochondrial Chain: H
Molecule details ›
Chain: H
Length: 267 amino acids
Theoretical weight: 30.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYD2 (Residues: 1-267; Coverage: 100%)
Gene name: MRPL9
Sequence domains: Ribosomal protein L9, N-terminal domain
39S ribosomal protein L10, mitochondrial Chain: I
Molecule details ›
Chain: I
Length: 261 amino acids
Theoretical weight: 29.32 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q7Z7H8 (Residues: 1-261; Coverage: 100%)
Gene names: MRPL10, MRPL8, RPML8
Sequence domains: Ribosomal protein L10
39S ribosomal protein L11, mitochondrial Chain: J
Molecule details ›
Chain: J
Length: 192 amino acids
Theoretical weight: 20.72 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3B7 (Residues: 1-192; Coverage: 100%)
Gene names: CGI-113, MRPL11
Sequence domains:
39S ribosomal protein L13, mitochondrial Chain: K
Molecule details ›
Chain: K
Length: 177 amino acids
Theoretical weight: 20.63 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYD1 (Residues: 2-178; Coverage: 99%)
Gene name: MRPL13
Sequence domains: Ribosomal protein L13
39S ribosomal protein L14, mitochondrial Chain: L
Molecule details ›
Chain: L
Length: 145 amino acids
Theoretical weight: 15.97 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q6P1L8 (Residues: 1-145; Coverage: 100%)
Gene names: MRPL14, MRPL32, RPML32
Sequence domains: Ribosomal protein L14p/L23e
39S ribosomal protein L15, mitochondrial Chain: M
Molecule details ›
Chain: M
Length: 296 amino acids
Theoretical weight: 33.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9P015 (Residues: 1-296; Coverage: 100%)
Gene names: HSPC145, MRPL15
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
39S ribosomal protein L16, mitochondrial Chain: N
Molecule details ›
Chain: N
Length: 251 amino acids
Theoretical weight: 28.5 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NX20 (Residues: 1-251; Coverage: 100%)
Gene names: MRPL16, PNAS-111
Sequence domains: Ribosomal protein L16p/L10e
39S ribosomal protein L17, mitochondrial Chain: O
Molecule details ›
Chain: O
Length: 175 amino acids
Theoretical weight: 20.08 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NRX2 (Residues: 1-175; Coverage: 100%)
Gene names: LIP2, MRPL17
Sequence domains: Ribosomal protein L17
39S ribosomal protein L18, mitochondrial Chain: P
Molecule details ›
Chain: P
Length: 180 amino acids
Theoretical weight: 20.61 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9H0U6 (Residues: 1-180; Coverage: 100%)
Gene names: HSPC071, MRPL18
Sequence domains: Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
39S ribosomal protein L19, mitochondrial Chain: Q
Molecule details ›
Chain: Q
Length: 292 amino acids
Theoretical weight: 33.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P49406 (Residues: 1-292; Coverage: 100%)
Gene names: KIAA0104, MRPL15, MRPL19
Sequence domains: Ribosomal protein L19
39S ribosomal protein L20, mitochondrial Chain: R
Molecule details ›
Chain: R
Length: 149 amino acids
Theoretical weight: 17.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYC9 (Residues: 1-149; Coverage: 100%)
Gene name: MRPL20
Sequence domains: Ribosomal protein L20
39S ribosomal protein L21, mitochondrial Chain: S
Molecule details ›
Chain: S
Length: 205 amino acids
Theoretical weight: 22.85 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q7Z2W9 (Residues: 1-205; Coverage: 100%)
Gene name: MRPL21
Sequence domains: Ribosomal prokaryotic L21 protein
39S ribosomal protein L22, mitochondrial Chain: T
Molecule details ›
Chain: T
Length: 206 amino acids
Theoretical weight: 23.68 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NWU5 (Residues: 1-206; Coverage: 100%)
Gene names: HSPC158, MRPL22, MRPL25, RPML25
Sequence domains: Ribosomal protein L22p/L17e
39S ribosomal protein L23, mitochondrial Chain: U
Molecule details ›
Chain: U
Length: 152 amino acids
Theoretical weight: 17.72 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q16540 (Residues: 2-153; Coverage: 99%)
Gene names: L23MRP, MRPL23, RPL23L
Sequence domains: Ribosomal protein L23
39S ribosomal protein L24, mitochondrial Chain: V
Molecule details ›
Chain: V
Length: 216 amino acids
Theoretical weight: 24.95 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96A35 (Residues: 1-216; Coverage: 100%)
Gene name: MRPL24
Sequence domains:
39S ribosomal protein L27, mitochondrial Chain: W
Molecule details ›
Chain: W
Length: 148 amino acids
Theoretical weight: 16.1 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9P0M9 (Residues: 1-148; Coverage: 100%)
Gene names: HSPC250, MRPL27
Sequence domains: Ribosomal L27 protein
39S ribosomal protein L28, mitochondrial Chain: X
Molecule details ›
Chain: X
Length: 256 amino acids
Theoretical weight: 30.2 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q13084 (Residues: 1-256; Coverage: 100%)
Gene names: MAAT1, MRPL28
Sequence domains: Ribosomal L28 family
39S ribosomal protein L47, mitochondrial Chain: Y
Molecule details ›
Chain: Y
Length: 250 amino acids
Theoretical weight: 29.51 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9HD33 (Residues: 1-250; Coverage: 100%)
Gene names: CGI-204, MRPL47, NCM1
Sequence domains: Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
39S ribosomal protein L30, mitochondrial Chain: Z
Molecule details ›
Chain: Z
Length: 161 amino acids
Theoretical weight: 18.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8TCC3 (Residues: 1-161; Coverage: 100%)
Gene names: HSPC249, MRPL28, MRPL30, RPML28
Sequence domains: Ribosomal protein L30p/L7e
39S ribosomal protein L32, mitochondrial Chain: 0
Molecule details ›
Chain: 0
Length: 188 amino acids
Theoretical weight: 21.44 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYC8 (Residues: 1-188; Coverage: 100%)
Gene names: HSPC283, MRPL32
Sequence domains: Ribosomal L32p protein family
39S ribosomal protein L33, mitochondrial Chain: 1
Molecule details ›
Chain: 1
Length: 65 amino acids
Theoretical weight: 7.64 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O75394 (Residues: 1-65; Coverage: 100%)
Gene names: C2orf1, MRPL33
Sequence domains: Ribosomal protein L33
39S ribosomal protein L34, mitochondrial Chain: 2
Molecule details ›
Chain: 2
Length: 92 amino acids
Theoretical weight: 10.18 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BQ48 (Residues: 1-92; Coverage: 100%)
Gene name: MRPL34
Sequence domains: Ribosomal protein L34
39S ribosomal protein L35, mitochondrial Chain: 3
Molecule details ›
Chain: 3
Length: 188 amino acids
Theoretical weight: 21.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NZE8 (Residues: 1-188; Coverage: 100%)
Gene names: BM-007, MRPL35
Sequence domains: Ribosomal protein L35
39S ribosomal protein L36, mitochondrial Chain: 4
Molecule details ›
Chain: 4
Length: 103 amino acids
Theoretical weight: 11.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9P0J6 (Residues: 1-103; Coverage: 100%)
Gene names: BRIP1, MRPL36
Sequence domains: Ribosomal protein L36
39S ribosomal protein L37, mitochondrial Chain: 5
Molecule details ›
Chain: 5
Length: 423 amino acids
Theoretical weight: 48.18 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BZE1 (Residues: 1-423; Coverage: 100%)
Gene names: HSPC235, MRPL2, MRPL37, RPML2
Sequence domains: Mitochondrial 28S ribosomal protein S30 (PDCD9)
39S ribosomal protein L38, mitochondrial Chain: 6
Molecule details ›
Chain: 6
Length: 380 amino acids
Theoretical weight: 44.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96DV4 (Residues: 1-380; Coverage: 100%)
Gene names: HSPC262, MRPL38
Sequence domains: Phosphatidylethanolamine-binding protein
39S ribosomal protein L39, mitochondrial Chain: 7
Molecule details ›
Chain: 7
Length: 338 amino acids
Theoretical weight: 38.76 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NYK5 (Residues: 1-338; Coverage: 100%)
Gene names: C21orf92, MRPL39, MRPL5, MSTP003, PRED22, RPML5
39S ribosomal protein L40, mitochondrial Chain: 8
Molecule details ›
Chain: 8
Length: 206 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NQ50 (Residues: 1-206; Coverage: 100%)
Gene names: MRPL40, NLVCF, URIM
Sequence domains: Mitochondrial ribosomal protein L28
39S ribosomal protein L41, mitochondrial Chain: 9
Molecule details ›
Chain: 9
Length: 137 amino acids
Theoretical weight: 15.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8IXM3 (Residues: 1-137; Coverage: 100%)
Gene names: BMRP, MRPL27, MRPL41, PIG3, RPML27
Sequence domains: Mitochondrial ribosomal protein L27
39S ribosomal protein L42, mitochondrial Chain: a
Molecule details ›
Chain: a
Length: 142 amino acids
Theoretical weight: 16.69 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y6G3 (Residues: 1-142; Coverage: 100%)
Gene names: HSPC204, MRPL31, MRPL42, MRPS32, PTD007, RPML31
Sequence domains: Mitochondrial 28S ribosomal protein S32
39S ribosomal protein L43, mitochondrial Chain: b
Molecule details ›
Chain: b
Length: 214 amino acids
Theoretical weight: 23.37 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8N983 (Residues: 2-215; Coverage: 100%)
Gene name: MRPL43
Sequence domains: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
39S ribosomal protein L44, mitochondrial Chain: c
Molecule details ›
Chain: c
Length: 332 amino acids
Theoretical weight: 37.58 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9H9J2 (Residues: 1-332; Coverage: 100%)
Gene name: MRPL44
39S ribosomal protein L45, mitochondrial Chain: d
Molecule details ›
Chain: d
Length: 306 amino acids
Theoretical weight: 35.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BRJ2 (Residues: 1-306; Coverage: 100%)
Gene name: MRPL45
Sequence domains: Tim44-like domain
39S ribosomal protein L46, mitochondrial Chain: e
Molecule details ›
Chain: e
Length: 279 amino acids
Theoretical weight: 31.75 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9H2W6 (Residues: 1-279; Coverage: 100%)
Gene names: C15orf4, LIECG2, MRPL46
Sequence domains: 39S mitochondrial ribosomal protein L46
39S ribosomal protein L48, mitochondrial Chain: f
Molecule details ›
Chain: f
Length: 212 amino acids
Theoretical weight: 23.97 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96GC5 (Residues: 1-212; Coverage: 100%)
Gene names: CGI-118, HSPC290, MRPL48
Sequence domains: Ribosomal protein S10p/S20e
39S ribosomal protein L49, mitochondrial Chain: g
Molecule details ›
Chain: g
Length: 166 amino acids
Theoretical weight: 19.23 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q13405 (Residues: 1-166; Coverage: 100%)
Gene names: C11orf4, MRPL49, NOF1, OK/SW-cl.67
39S ribosomal protein L50, mitochondrial Chain: h
Molecule details ›
Chain: h
Length: 158 amino acids
Theoretical weight: 18.35 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8N5N7 (Residues: 1-158; Coverage: 100%)
Gene name: MRPL50
39S ribosomal protein L51, mitochondrial Chain: i
Molecule details ›
Chain: i
Length: 128 amino acids
Theoretical weight: 15.13 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q4U2R6 (Residues: 1-128; Coverage: 100%)
Gene names: CDA09, HSPC241, MRP64, MRPL51
39S ribosomal protein L52, mitochondrial Chain: j
Molecule details ›
Chain: j
Length: 123 amino acids
Theoretical weight: 13.68 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q86TS9 (Residues: 1-123; Coverage: 100%)
Gene name: MRPL52
39S ribosomal protein L53, mitochondrial Chain: k
Molecule details ›
Chain: k
Length: 111 amino acids
Theoretical weight: 12.04 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96EL3 (Residues: 2-112; Coverage: 99%)
Gene name: MRPL53
39S ribosomal protein L54, mitochondrial Chain: l
Molecule details ›
Chain: l
Length: 138 amino acids
Theoretical weight: 15.84 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q6P161 (Residues: 1-138; Coverage: 100%)
Gene name: MRPL54
39S ribosomal protein L55, mitochondrial Chain: m
Molecule details ›
Chain: m
Length: 128 amino acids
Theoretical weight: 15.16 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q7Z7F7 (Residues: 1-128; Coverage: 100%)
Gene names: MRPL55, UNQ5835/PRO19675
Ribosomal protein 63, mitochondrial Chain: o
Molecule details ›
Chain: o
Length: 102 amino acids
Theoretical weight: 12.29 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BQC6 (Residues: 1-102; Coverage: 100%)
Gene names: MRP63, MRPL57
Peptidyl-tRNA hydrolase ICT1, mitochondrial Chain: p
Molecule details ›
Chain: p
Length: 206 amino acids
Theoretical weight: 23.67 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q14197 (Residues: 1-206; Coverage: 100%)
Gene names: DS1, ICT1, MRPL58
Growth arrest and DNA damage-inducible proteins-interacting protein 1 Chain: q
Molecule details ›
Chain: q
Length: 222 amino acids
Theoretical weight: 25.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q8TAE8 (Residues: 1-222; Coverage: 100%)
Gene names: GADD45GIP1, MRPL59, PLINP1, PRG6
39S ribosomal protein S18a, mitochondrial Chain: r
Molecule details ›
Chain: r
Length: 196 amino acids
Theoretical weight: 22.22 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NVS2 (Residues: 1-196; Coverage: 100%)
Gene name: MRPS18A
39S ribosomal protein S30, mitochondrial Chain: s
Molecule details ›
Chain: s
Length: 439 amino acids
Theoretical weight: 50.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NP92 (Residues: 1-439; Coverage: 100%)
Gene names: BM-047, MRPS30, PDCD9
39S ribosomal protein L12, mitochondrial Chains: t1, t2, t3, t4, t5, t6
Molecule details ›
Chains: t1, t2, t3, t4, t5, t6
Length: 198 amino acids
Theoretical weight: 21.38 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P52815 (Residues: 1-198; Coverage: 100%)
Gene names: MRPL12, MRPL7, RPML12
28S ribosomal protein S2, mitochondrial Chain: AB
Molecule details ›
Chain: AB
Length: 296 amino acids
Theoretical weight: 33.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y399 (Residues: 1-296; Coverage: 100%)
Gene names: CGI-91, MRPS2
28S ribosomal protein S24, mitochondrial Chain: AC
Molecule details ›
Chain: AC
Length: 167 amino acids
Theoretical weight: 19.05 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96EL2 (Residues: 1-167; Coverage: 100%)
Gene names: HSPC335, MRPS24
28S ribosomal protein S5, mitochondrial Chain: AD
Molecule details ›
Chain: AD
Length: 430 amino acids
Theoretical weight: 48.09 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82675 (Residues: 1-430; Coverage: 100%)
Gene name: MRPS5
28S ribosomal protein S6, mitochondrial Chain: AE
Molecule details ›
Chain: AE
Length: 125 amino acids
Theoretical weight: 14.25 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82932 (Residues: 1-125; Coverage: 100%)
Gene names: C21orf101, MRPS6, RPMS6
28S ribosomal protein S7, mitochondrial Chain: AF
Molecule details ›
Chain: AF
Length: 242 amino acids
Theoretical weight: 28.19 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y2R9 (Residues: 1-242; Coverage: 100%)
Gene name: MRPS7
28S ribosomal protein S9, mitochondrial Chain: AG
Molecule details ›
Chain: AG
Length: 396 amino acids
Theoretical weight: 45.91 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82933 (Residues: 1-396; Coverage: 100%)
Gene names: MRPS9, RPMS9
28S ribosomal protein S10, mitochondrial Chain: AH
Molecule details ›
Chain: AH
Length: 201 amino acids
Theoretical weight: 23.03 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82664 (Residues: 1-201; Coverage: 100%)
Gene names: MRPS10, MSTP040
28S ribosomal protein S11, mitochondrial Chain: AI
Molecule details ›
Chain: AI
Length: 194 amino acids
Theoretical weight: 20.65 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82912 (Residues: 1-194; Coverage: 100%)
Gene names: HCC2, MRPS11, RPMS11
28S ribosomal protein S12, mitochondrial Chain: AJ
Molecule details ›
Chain: AJ
Length: 138 amino acids
Theoretical weight: 15.2 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O15235 (Residues: 1-138; Coverage: 100%)
Gene names: MRPS12, RPMS12, RPSM12
28S ribosomal protein S14, mitochondrial Chain: AK
Molecule details ›
Chain: AK
Length: 128 amino acids
Theoretical weight: 15.17 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: O60783 (Residues: 1-128; Coverage: 100%)
Gene name: MRPS14
28S ribosomal protein S15, mitochondrial Chain: AL
Molecule details ›
Chain: AL
Length: 257 amino acids
Theoretical weight: 29.9 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82914 (Residues: 1-257; Coverage: 100%)
Gene names: DC37, MRPS15, RPMS15
28S ribosomal protein S16, mitochondrial Chain: AM
Molecule details ›
Chain: AM
Length: 137 amino acids
Theoretical weight: 15.37 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3D3 (Residues: 1-137; Coverage: 100%)
Gene names: CGI-132, MRPS16, RPMS16
28S ribosomal protein S17, mitochondrial Chain: AN
Molecule details ›
Chain: AN
Length: 130 amino acids
Theoretical weight: 14.53 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y2R5 (Residues: 1-130; Coverage: 100%)
Gene names: HSPC011, MRPS17, RPMS17
28S ribosomal protein S18b, mitochondrial Chain: AO
Molecule details ›
Chain: AO
Length: 258 amino acids
Theoretical weight: 29.44 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y676 (Residues: 1-258; Coverage: 100%)
Gene names: C6orf14, HSPC183, MRPS18B, PTD017
28S ribosomal protein S18c, mitochondrial Chain: AP
Molecule details ›
Chain: AP
Length: 142 amino acids
Theoretical weight: 15.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3D5 (Residues: 1-142; Coverage: 100%)
Gene names: CGI-134, MRPS18C
28S ribosomal protein S21, mitochondrial Chain: AQ
Molecule details ›
Chain: AQ
Length: 86 amino acids
Theoretical weight: 10.68 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82921 (Residues: 2-87; Coverage: 99%)
Gene names: MDS016, MRPS21, RPMS21
28S ribosomal protein S22, mitochondrial Chain: AR
Molecule details ›
Chain: AR
Length: 360 amino acids
Theoretical weight: 41.34 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82650 (Residues: 1-360; Coverage: 100%)
Gene names: C3orf5, GK002, MRPS22, RPMS22
28S ribosomal protein S23, mitochondrial Chain: AS
Molecule details ›
Chain: AS
Length: 190 amino acids
Theoretical weight: 21.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3D9 (Residues: 1-190; Coverage: 100%)
Gene names: CGI-138, HSPC329, MRPS23
28S ribosomal protein S25, mitochondrial Chain: AT
Molecule details ›
Chain: AT
Length: 173 amino acids
Theoretical weight: 20.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82663 (Residues: 1-173; Coverage: 100%)
Gene names: MRPS25, RPMS25
28S ribosomal protein S26, mitochondrial Chain: AU
Molecule details ›
Chain: AU
Length: 205 amino acids
Theoretical weight: 24.26 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BYN8 (Residues: 1-205; Coverage: 100%)
Gene names: C20orf193, MRPS26, RPMS13
28S ribosomal protein S27, mitochondrial Chain: AV
Molecule details ›
Chain: AV
Length: 414 amino acids
Theoretical weight: 47.67 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q92552 (Residues: 1-414; Coverage: 100%)
Gene names: KIAA0264, MRPS27
28S ribosomal protein S28, mitochondrial Chain: AW
Molecule details ›
Chain: AW
Length: 187 amino acids
Theoretical weight: 20.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y2Q9 (Residues: 1-187; Coverage: 100%)
Gene names: HSPC007, MRPS28, MRPS35
28S ribosomal protein S29, mitochondrial Chain: AX
Molecule details ›
Chain: AX
Length: 398 amino acids
Theoretical weight: 45.63 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P51398 (Residues: 1-398; Coverage: 100%)
Gene names: DAP3, MRPS29
28S ribosomal protein S31, mitochondrial Chain: AY
Molecule details ›
Chain: AY
Length: 395 amino acids
Theoretical weight: 45.39 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q92665 (Residues: 1-395; Coverage: 100%)
Gene names: IMOGN38, MRPS31
28S ribosomal protein S33, mitochondrial Chain: AZ
Molecule details ›
Chain: AZ
Length: 106 amino acids
Theoretical weight: 12.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y291 (Residues: 1-106; Coverage: 100%)
Gene names: CGI-139, MRPS33, PTD003
28S ribosomal protein S34, mitochondrial Chain: A0
Molecule details ›
Chain: A0
Length: 218 amino acids
Theoretical weight: 25.7 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82930 (Residues: 1-218; Coverage: 100%)
Gene name: MRPS34
28S ribosomal protein S35, mitochondrial Chain: A1
Molecule details ›
Chain: A1
Length: 323 amino acids
Theoretical weight: 36.9 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P82673 (Residues: 1-323; Coverage: 100%)
Gene names: HDCMD11P, MDS023, MRPS28, MRPS35, PSEC0213
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 Chain: A2
Molecule details ›
Chain: A2
Length: 117 amino acids
Theoretical weight: 13.41 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96BP2 (Residues: 2-118; Coverage: 99%)
Gene names: C10orf34, CHCHD1, MRPS37
Aurora kinase A-interacting protein Chain: A3
Molecule details ›
Chain: A3
Length: 199 amino acids
Theoretical weight: 22.4 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9NWT8 (Residues: 1-199; Coverage: 100%)
Gene names: AIP, AKIP, AURKAIP1, MRPS38
Pentatricopeptide repeat domain-containing protein 3, mitochondrial Chain: A4
Molecule details ›
Chain: A4
Length: 689 amino acids
Theoretical weight: 78.65 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q96EY7 (Residues: 1-689; Coverage: 100%)
Gene names: MRPS39, PTCD3, TRG15
16S mitochondrial rRNA Chain: A
Molecule details ›
Chain: A
Length: 1561 nucleotides
Theoretical weight: 500.67 KDa
mitochondrial tRNAVal Chain: B
Molecule details ›
Chain: B
Length: 72 nucleotides
Theoretical weight: 22.96 KDa
12S mitochondrial rRNA Chain: AA
Molecule details ›
Chain: AA
Length: 954 nucleotides
Theoretical weight: 306.12 KDa
A-site tRNA Chain: w
Molecule details ›
Chain: w
Length: 68 nucleotides
Theoretical weight: 21.68 KDa
P-site tRNA Chain: x
Molecule details ›
Chain: x
Length: 70 nucleotides
Theoretical weight: 22.37 KDa
Messenger RNA Chain: y
Molecule details ›
Chain: y
Length: 19 nucleotides
Theoretical weight: 6 KDa

Ligands and Environments

6 bound ligands:
Ligand MG 189 x MG
Ligand K 44 x K
Ligand ZN 3 x ZN
Ligand FES 3 x FES
Ligand ATP 1 x ATP
Ligand GTP 1 x GTP
4 modified residues:
Ligand SAC 1 x SAC
Ligand AYA 4 x AYA
Ligand THC 1 x THC
Ligand IAS 1 x IAS

Experiments and Validation Details

Entry percentile scores
Resolution: 2.59Å
Relevant EMDB volumes: EMD-11279

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