› 6zj8

X-ray diffraction
2.4Å resolution

Structure of the PAS domain from Bordetella pertussis BvgS

Released:
DOI: 10.2210/pdb6zj8/pdb
PDB entry 6zj8 coloured by chain, front view.
PDB entry 6zj8 coloured by chain, side view.
PDB entry 6zj8 coloured by chain, top view.
Source organism: Bordetella pertussis Tohama I
Primary publication:
Structural insight into the role of the PAS domainfor signal transduction in sensor-kinase BvgS.
Dupré E, Clantin B, Yuan Y, Lecher S, Lesne E, Antoine R, Villeret V, Jacob-Dubuisson F
J Bacteriol 203 (2021)
PMID: 33619154

Function and Biology Details

Reaction catalysed: 
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147769 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Virulence sensor protein BvgS Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 162 amino acids
Theoretical weight: 18.33 KDa
Source organism: Bordetella pertussis Tohama I
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P16575 (Residues: 550-550, 573-720; Coverage: 12%)
Gene names: BP1877, bvgS
Sequence domains: PAS fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21212
Unit cell:
a: 121.96Å b: 122.288Å c: 105.283Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.227 0.252
Expression system: Escherichia coli BL21

Quick links

Citations

1 review citation

Nitrate- and Nitrite-Sensing Histidine Kinases: Function, Structure, and Natural Diversity.
Gushchin et al. (2021)

2 mentions without citation

Acid-Sensing Histidine Kinase With a Redox Switch.
Inada et al. (2021)
1 more