6zgu

X-ray diffraction
2.18Å resolution

Crystal structure of a MFS transporter with bound 3-(2-methylphenyl)propanoic acid at 2.41 Angstroem resolution

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
L-lactate transporter Chains: A, B
Molecule details ›
Chains: A, B
Length: 420 amino acids
Theoretical weight: 44.8 KDa
Source organism: Syntrophobacter fumaroxidans MPOB
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A0LNN5 (Residues: 1-412; Coverage: 100%)
Gene name: Sfum_3364
Sequence domains: Major Facilitator Superfamily

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21212
Unit cell:
a: 102.048Å b: 199.703Å c: 61.616Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.216 0.244
Expression system: Escherichia coli BL21(DE3)