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H11-H4 complex with SARS-CoV-2

X-ray diffraction
1.85Å resolution
PDB entry 6zbp coloured by chain, front view.
PDB entry 6zbp coloured by chain, side view.
PDB entry 6zbp coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Spike protein S2' and IG-heavy chain
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Multimeric state: hetero dimer
Accessible surface area: 16069.36 Å2
Buried surface area: 1708.58 Å2
Dissociation area: 643.83 Å2
Dissociation energy (ΔGdiss): -5.38 kcal/mol
Dissociation entropy (TΔSdiss): 11.67 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-209684

Macromolecules

Spike protein S1
Chain: EEE
Length: 210 amino acids
Theoretical weight: 23.72 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 330-532; Coverage: 16%)
Gene names: 2, S
Pfam: Betacoronavirus spike glycoprotein S1, receptor binding
InterPro:
Spike protein S1 in PDB entry 6zbp, assembly 1, front view.
Spike protein S1 in PDB entry 6zbp, assembly 1, side view.
Spike protein S1 in PDB entry 6zbp, assembly 1, top view.
Molecule details ›

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H11-H4
Chain: FFF
Length: 134 amino acids
Theoretical weight: 15.05 KDa
Source organism: Lama glama
Expression system: Escherichia coli
InterPro:
H11-H4 in PDB entry 6zbp, assembly 1, front view.
H11-H4 in PDB entry 6zbp, assembly 1, side view.
H11-H4 in PDB entry 6zbp, assembly 1, top view.
Molecule details ›

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