› 6z2c

X-ray diffraction
1.8Å resolution

Engineered lipocalin C3A5 in complex with a transition state analog

Released:
DOI: 10.2210/pdb6z2c/pdb
PDB 6z2c coloured by chain and viewed from the front.
PDB 6z2c coloured by chain and viewed from the side.
PDB 6z2c coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Skerra A, Eichinger A

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil gelatinase-associated lipocalin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 188 amino acids
Theoretical weight: 21.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P80188 (Residues: 21-198; Coverage: 100%)
Gene names: HNL, LCN2, NGAL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family

Ligands and Environments

1 bound ligand:
Ligand Q5E 3 x Q5E
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P2
Unit cell:
a: 96.385Å b: 39.034Å c: 96.385Å
α: 90° β: 120° γ: 90°
R-values:
R R work R free
0.162 0.161 0.19
Expression system: Escherichia coli

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