Function and Biology Details
Reaction catalysed:
(2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate = n diphosphate + ditrans,polycis-polyprenyl diphosphate (n = 10-55)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Dehydrodolichyl diphosphate synthase complex (preferred)
PDBe Complex ID:
PDB-CPX-183153 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Dehydrodolichyl diphosphate synthase complex subunit DHDDS
Molecule details ›
Chain: A
Length: 340 amino acids
Theoretical weight: 39.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Putative undecaprenyl diphosphate synthase
Length: 340 amino acids
Theoretical weight: 39.2 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q86SQ9 (Residues: 1-333; Coverage: 100%)
Sequence domains: Putative undecaprenyl diphosphate synthase
Dehydrodolichyl diphosphate synthase complex subunit NUS1
Molecule details ›
Chain: B
Length: 219 amino acids
Theoretical weight: 24.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Putative undecaprenyl diphosphate synthase
Length: 219 amino acids
Theoretical weight: 24.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q96E22 (Residues: 73-293; Coverage: 72%)
Sequence domains: Putative undecaprenyl diphosphate synthase
