X-ray diffraction
3Å resolution

Human Eg5 motor domain mutant R234C

Source organism: Homo sapiens
Entry authors: Garcia-Saez I, Skoufias DA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Kinesin-like protein KIF11 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 368 amino acids
Theoretical weight: 41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P52732 (Residues: 1-368; Coverage: 35%)
Gene names: EG5, KIF11, KNSL1, TRIP5
Sequence domains: Kinesin motor domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 87.428Å b: 87.603Å c: 95.065Å
α: 90° β: 116.82° γ: 90°
R R work R free
0.274 0.272 0.306
Expression system: Escherichia coli