X-ray diffraction
2.4Å resolution

Crystal structure of Atg16L in complex with GTP-bound Rab33B (Q92L)


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras-related protein Rab-33B Chains: A, B
Molecule details ›
Chains: A, B
Length: 192 amino acids
Theoretical weight: 21.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q9H082 (Residues: 30-218; Coverage: 83%)
Gene name: RAB33B
Sequence domains: Ras family
Autophagy-related protein 16-1 Chains: C, D
Molecule details ›
Chains: C, D
Length: 126 amino acids
Theoretical weight: 14.53 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q8C0J2 (Residues: 141-265; Coverage: 21%)
Gene names: Apg16l, Atg16l1

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P212121
Unit cell:
a: 56.95Å b: 132.42Å c: 155.13Å
α: 90° β: 90° γ: 90°
R R work R free
0.194 0.192 0.231
Expression system: Escherichia coli BL21(DE3)