› 6xuj

X-ray diffraction
1.54Å resolution

HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21212

Released:
DOI: 10.2210/pdb6xuj/pdb
PDB 6xuj coloured by chain and viewed from the front.
PDB 6xuj coloured by chain and viewed from the side.
PDB 6xuj coloured by chain and viewed from the top.
Source organism: Pyrococcus furiosus DSM 3638
Entry authors: Marsh ME, Scott DE, Hyvonen M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair and recombination protein RadA Chain: A
Molecule details ›
Chain: A
Length: 231 amino acids
Theoretical weight: 25.5 KDa
Source organism: Pyrococcus furiosus DSM 3638
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O74036 (Residues: 108-349; Coverage: 66%)
Gene names: PF1926, radA
Sequence domains: Rad51

Ligands and Environments

2 bound ligands:
Ligand PO4 1 x PO4
Ligand O1E 1 x O1E
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21212
Unit cell:
a: 69.453Å b: 73.211Å c: 40.793Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.166 0.205
Expression system: Escherichia coli BL21(DE3)

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