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X-ray diffraction
1.54Å resolution

HumRadA1 in complex with 5-Ethyl-N-(1H-indol-5-ylmethyl)-1,3,4-thiadiazol-2-amine in P21212

Released:
Source organism: Pyrococcus furiosus DSM 3638
Entry authors: Marsh ME, Scott DE, Hyvonen M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA repair and recombination protein RadA Chain: A
Molecule details ›
Chain: A
Length: 231 amino acids
Theoretical weight: 25.5 KDa
Source organism: Pyrococcus furiosus DSM 3638
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O74036 (Residues: 108-349; Coverage: 66%)
Gene names: PF1926, radA
Sequence domains: Rad51

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21212
Unit cell:
a: 69.453Å b: 73.211Å c: 40.793Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.166 0.205
Expression system: Escherichia coli BL21(DE3)