› 6xqj

Solution NMR

Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A

Released:
DOI: 10.2210/pdb6xqj/pdb
PDB entry 6xqj coloured by chain, ensemble of 55 models, front view.
PDB entry 6xqj coloured by chain, ensemble of 55 models, side view.
PDB entry 6xqj coloured by chain, ensemble of 55 models, top view.
Source organisms:
Primary publication:
Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A.
Byeon IL, Calero G, Wu Y, Byeon CH, Jung J, DeLucia M, Zhou X, Weiss S, Ahn J, Hao C, Skowronski J, Gronenborn AM
Nat Commun 12 6864 (2021)
PMID: 34824204

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146250 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein Vpr; UV excision repair protein RAD23 homolog A Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 26.79 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: P12520 (Residues: 1-79; Coverage: 82%)
  • Canonical: P54725 (Residues: 223-363; Coverage: 39%)
Gene names: RAD23A, vpr
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 80%
Refinement method: simulated annealing
Expression system: Escherichia coli

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