6xiy

X-ray diffraction
2.31Å resolution

Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to methyl 2-(acetylamino)-2-deoxy-1-thio-alpha-D-galactopyranose

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
C-type lectin domain family 10 member A Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IUN9 (Residues: 181-308; Coverage: 41%)
Gene names: CLEC10A, CLECSF13, CLECSF14, HML
Sequence domains: Lectin C-type domain

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID30B
Spacegroup: P3121
Unit cell:
a: 52.289Å b: 52.289Å c: 113.274Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.166 0.162 0.202
Expression system: Escherichia coli