6xdg

Electron Microscopy
3.9Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (6 distinct):
Spike protein S1 Chain: E
Molecule details ›
Chain: E
Length: 251 amino acids
Theoretical weight: 28.44 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P0DTC2 (Residues: 319-541; Coverage: 18%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
REGN10933 antibody Fab fragment light chain Chain: D
Molecule details ›
Chain: D
Length: 214 amino acids
Theoretical weight: 23.35 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
REGN10933 antibody Fab fragment heavy chain Chain: B
Molecule details ›
Chain: B
Length: 226 amino acids
Theoretical weight: 24.14 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
REGN10987 antibody Fab fragment heavy chain Chain: C
Molecule details ›
Chain: C
Length: 225 amino acids
Theoretical weight: 24.04 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
REGN10987 antibody Fab fragment light chain Chain: A
Molecule details ›
Chain: A
Length: 216 amino acids
Theoretical weight: 22.8 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-22137
Expression system: Cricetulus griseus