6xcl

X-ray diffraction
2.7Å resolution

Crystal Structure of human telomeric DNA G-quadruplex in complex with a novel platinum(II) complex.

Released:
Source organism: Homo sapiens
Entry authors: Miron CE, van Staalduinen LM, Jia Z, Petitjean A

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 22 nucleotides
Theoretical weight: 6.98 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08B1-1
Spacegroup: P3
Unit cell:
a: 64.03Å b: 64.03Å c: 42.23Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.191 0.243
Expression system: Not provided