› 6x20

X-ray diffraction
1.4Å resolution

PDZ domain from choanoflagellate GIPC (mbGIPC) bound to B1AR peptide

Released:
DOI: 10.2210/pdb6x20/pdb
PDB entry 6x20 coloured by chain, front view.
PDB entry 6x20 coloured by chain, side view.
PDB entry 6x20 coloured by chain, top view.
Source organism: Monosiga brevicollis
Primary publication:
Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Gao M, Mackley IGP, Mesbahi-Vasey S, Bamonte HA, Struyvenberg SA, Landolt L, Pederson NJ, Williams LI, Bahl CD, Brooks L, Amacher JF
Protein Sci 29 2226-2244 (2020)
PMID: 32914530

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109052 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PDZ domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 96 amino acids
Theoretical weight: 10.35 KDa
Source organism: Monosiga brevicollis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A9VCZ3 (Residues: 94-183; Coverage: 31%)
Gene name: MONBRDRAFT_39217
Sequence domains: PDZ domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P212121
Unit cell:
a: 29.787Å b: 34.841Å c: 81.604Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.209 0.208 0.226
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 citations in other articles

Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets.
Tahti et al. (2023)

3 mentions without citation

Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.
Hoffmann-Eßer et al. (2017)
2 more