› 6wwd

X-ray diffraction
2.1Å resolution

Crystal structure of Nucleoside-triphosphatase / dITP/XTP pyrophosphatase from Mycobacterium abscessus ATCC 19977 / DSM 44196

Released:
DOI: 10.2210/pdb6wwd/pdb
PDB entry 6wwd coloured by chain, front view.
PDB entry 6wwd coloured by chain, side view.
PDB entry 6wwd coloured by chain, top view.
Source organism: Mycobacteroides abscessus ATCC 19977
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Reaction catalysed: 
ITP + H(2)O = IMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-109375 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dITP/XTP pyrophosphatase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 213 amino acids
Theoretical weight: 22.7 KDa
Source organism: Mycobacteroides abscessus ATCC 19977
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: B1MLZ4 (Residues: 1-206; Coverage: 100%)
Gene name: MAB_1485
Sequence domains: Ham1 family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 50.69Å b: 104.04Å c: 146.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.186 0.244
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

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