› 6wvm

Electron Microscopy
3.3Å resolution

High curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule

Released:
DOI: 10.2210/pdb6wvm/pdb
PDB 6wvm coloured by chain and viewed from the front.
PDB 6wvm coloured by chain and viewed from the side.
PDB 6wvm coloured by chain and viewed from the top.
Source organism: Bos taurus
Primary publication:
Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy.
Debs GE, Cha M, Liu X, Huehn AR, Sindelar CV
Proc. Natl. Acad. Sci. U.S.A. (2020)
PMID: 32636254
Related structures: EMD-21923

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tubulin alpha-1B chain Chains: A, C
Molecule details ›
Chains: A, C
Length: 451 amino acids
Theoretical weight: 50.2 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P81947 (Residues: 1-451; Coverage: 100%)
Sequence domains:
Tubulin beta-2B chain Chains: B, D
Molecule details ›
Chains: B, D
Length: 445 amino acids
Theoretical weight: 49.95 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: Q6B856 (Residues: 1-445; Coverage: 100%)
Gene name: TUBB2B
Sequence domains:

Ligands and Environments

4 bound ligands:
Ligand GTP 2 x GTP
Ligand MG 2 x MG
Ligand GDP 2 x GDP
Ligand TA1 2 x TA1
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-21923

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