X-ray diffraction
2.19Å resolution

Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with tryptophan substrate and SAM analog (aza-SAM) bound


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Tryptophanase Chains: A, B
Molecule details ›
Chains: A, B
Length: 575 amino acids
Theoretical weight: 64.14 KDa
Source organism: Kitasatospora setae KM-6054
Expression system: Escherichia coli
  • Canonical: E4N8S5 (Residues: 1-575; Coverage: 100%)
Gene name: KSE_17820
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P21
Unit cell:
a: 50.355Å b: 103.085Å c: 105.757Å
α: 90° β: 94.77° γ: 90°
R R work R free
0.213 0.211 0.249
Expression system: Escherichia coli