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Crystal structure of a soluble variant of full-length human APOBEC3G (pH 8.0)

X-ray diffraction
3.02Å resolution
PDB entry 6wmb coloured by chain, front view.
PDB entry 6wmb coloured by chain, side view.
PDB entry 6wmb coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 1 distinct polypeptide molecule
1 distinct DNA molecule

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 19547.26 Å2
Buried surface area: 778.16 Å2
Dissociation area: 338.29 Å2
Dissociation energy (ΔGdiss): -2.02 kcal/mol
Dissociation entropy (TΔSdiss): 5.59 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-120850

Macromolecules

APOLIPOPROTEIN B MRNA EDITING ENZYME, CATALYTIC PEPTIDE- LIKE 3G
Chain: A
Length: 367 amino acids
Theoretical weight: 42.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
InterPro:
APOLIPOPROTEIN B MRNA EDITING ENZYME, CATALYTIC PEPTIDE- LIKE 3G in PDB entry 6wmb, assembly 1, front view.
APOLIPOPROTEIN B MRNA EDITING ENZYME, CATALYTIC PEPTIDE- LIKE 3G in PDB entry 6wmb, assembly 1, side view.
APOLIPOPROTEIN B MRNA EDITING ENZYME, CATALYTIC PEPTIDE- LIKE 3G in PDB entry 6wmb, assembly 1, top view.
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DNA chain B
Name: DNA (5'-D(P*CP*C)-3')
Representative chains: B
Source organism: Escherichia coli [562]
Expression system: Escherichia coli [562]
Length: 2 nucleotides
Theoretical weight: 533 Da
DNA (5'-D(P*CP*C)-3') in PDB entry 6wmb, assembly 1, front view.
DNA (5'-D(P*CP*C)-3') in PDB entry 6wmb, assembly 1, side view.
DNA (5'-D(P*CP*C)-3') in PDB entry 6wmb, assembly 1, top view.
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