6wmb

X-ray diffraction
3.02Å resolution

Crystal structure of a soluble variant of full-length human APOBEC3G (pH 8.0)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
APOLIPOPROTEIN B MRNA EDITING ENZYME, CATALYTIC PEPTIDE- LIKE 3G Chain: A
Molecule details ›
Chain: A
Length: 367 amino acids
Theoretical weight: 42.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
DNA (5'-D(P*CP*C)-3') Chain: B
Molecule details ›
Chain: B
Length: 2 nucleotides
Theoretical weight: 533 Da
Source organism: Escherichia coli
Expression system: Escherichia coli

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Unit cell:
a: 60.238Å b: 42.081Å c: 194.21Å
α: 90° β: 95.759° γ: 90°
R-values:
R R work R free
0.253 0.247 0.305
Expression system: Escherichia coli