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Crystal structure of Glutamate-1-semialdehyde 2,1-aminomutase from Stenotrophomonas maltophilia K279a in complex with PLP

Source organism: Stenotrophomonas maltophilia K279a
Biochemical function: glutamate-1-semialdehyde 2,1-aminomutase activity
Biological process: tetrapyrrole biosynthetic process
Cellular component: cytoplasm

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EC 5.4.3.8: Glutamate-1-semialdehyde 2,1-aminomutase

Reaction catalysed:
(S)-4-amino-5-oxopentanoate = 5-aminolevulinate
Systematic name:
(S)-4-amino-5-oxopentanoate 4,5-aminomutase
Alternative Name(s):
  • Glutamate-1-semialdehyde aminotransferase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF00202
Domain description: Aminotransferase class-III
Occurring in:
  1. Glutamate-1-semialdehyde 2,1-aminomutase
The deposited structure of PDB entry 6w80 contains 1 copy of Pfam domain PF00202 (Aminotransferase class-III) in Glutamate-1-semialdehyde 2,1-aminomutase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR005814
Domain description: Aminotransferase class-III
Occurring in:
  1. Glutamate-1-semialdehyde 2,1-aminomutase
IPR004639
Domain description: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase
Occurring in:
  1. Glutamate-1-semialdehyde 2,1-aminomutase
IPR015421
Domain description: Pyridoxal phosphate-dependent transferase, major domain
Occurring in:
  1. Glutamate-1-semialdehyde 2,1-aminomutase
IPR015422
Domain description: Pyridoxal phosphate-dependent transferase, small domain
Occurring in:
  1. Glutamate-1-semialdehyde 2,1-aminomutase
IPR015424
Domain description: Pyridoxal phosphate-dependent transferase
Occurring in:
  1. Glutamate-1-semialdehyde 2,1-aminomutase

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