› 6w4l

X-ray diffraction
1.31Å resolution

The crystal structure of a single chain H2B-H2A histone chimera from Xenopus laevis

Released:
DOI: 10.2210/pdb6w4l/pdb
PDB 6w4l coloured by chain and viewed from the front.
PDB 6w4l coloured by chain and viewed from the side.
PDB 6w4l coloured by chain and viewed from the top.
Source organism: Xenopus laevis
Primary publication:
Structure of a single-chain H2A/H2B dimer.
Warren C, Bonanno JB, Almo SC, Shechter D
Acta Crystallogr F Struct Biol Commun 76 194-198 (2020)
PMID: 32356520

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Histone H2A type 1; Histone H2B 1.1 Chain: A
Molecule details ›
Chain: A
Length: 186 amino acids
Theoretical weight: 20.52 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P02281 (Residues: 34-126; Coverage: 74%)
  • Canonical: P06897 (Residues: 14-105; Coverage: 71%)
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand PPV 1 x PPV
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: C2
Unit cell:
a: 61.793Å b: 44.679Å c: 66.45Å
α: 90° β: 117.27° γ: 90°
R-values:
R R work R free
0.171 0.17 0.206
Expression system: Escherichia coli BL21(DE3)

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