6vw9

X-ray diffraction
1.8Å resolution

C-terminal regulatory domain of the chloride transporter KCC-1 from C. elegans, proteolyzed during crystallization

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
K+/Cl-Cotransporter Chain: A
Molecule details ›
Chain: A
Length: 233 amino acids
Theoretical weight: 26.44 KDa
Source organism: Caenorhabditis elegans
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: S6FCX2 (Residues: 661-892; Coverage: 22%)
Gene names: CELE_R13A1.2, R13A1.2, kcc-1
Sequence domains: Solute carrier family 12
K+/Cl-Cotransporter Chain: B
Molecule details ›
Chain: B
Length: 71 amino acids
Theoretical weight: 8.11 KDa
Source organism: Caenorhabditis elegans
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: S6FCX2 (Residues: 996-1066; Coverage: 7%)
Gene names: CELE_R13A1.2, R13A1.2, kcc-1
Sequence domains: Solute carrier family 12

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 104.32Å b: 65.546Å c: 56.523Å
α: 90° β: 97.174° γ: 90°
R-values:
R R work R free
0.184 0.183 0.214
Expression system: Spodoptera frugiperda