6vu8

Electron Microscopy
4.14Å resolution

Structure of G-alpha-i bound to its chaperone Ric-8A

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-109301 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Synembryn Chain: A
Molecule details ›
Chain: A
Length: 534 amino acids
Theoretical weight: 60.51 KDa
Source organism: Rattus norvegicus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: B1H241 (Residues: 1-530; Coverage: 100%)
Gene name: Ric8a
Sequence domains: Guanine nucleotide exchange factor synembryn
Guanine nucleotide-binding protein G(i) subunit alpha-1 Chain: B
Molecule details ›
Chain: B
Length: 359 amino acids
Theoretical weight: 41.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P63096 (Residues: 2-119, 120-354; Coverage: 100%)
Gene name: GNAI1
Sequence domains: G-protein alpha subunit

Ligands and Environments

No bound ligands
2 modified residues:

Experiments and Validation Details

Entry percentile scores
Resolution: 4.14Å
Relevant EMDB volumes: EMD-21388
Expression systems:
  • Trichoplusia ni
  • Escherichia coli