6vlr

Electron Microscopy
4.42Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
Non-polymer only tetradecamer (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (11 distinct):
Envelope glycoprotein gp160 Chains: A, G, H
Molecule details ›
Chains: A, G, H
Length: 475 amino acids
Theoretical weight: 53.27 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 30-504; Coverage: 55%)
Gene name: env
Sequence domains: Envelope glycoprotein GP120
Transmembrane protein gp41 Chains: B, I, J
Molecule details ›
Chains: B, I, J
Length: 153 amino acids
Theoretical weight: 17.18 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Homo sapiens
UniProt:
  • Canonical: Q2N0S6 (Residues: 509-661; Coverage: 18%)
Gene name: env
PGT122 Fab Heavy Chain Chains: C, D, E
Molecule details ›
Chains: C, D, E
Length: 132 amino acids
Theoretical weight: 14.84 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
PGT122 Fab Light Chain Chains: K, L, M
Molecule details ›
Chains: K, L, M
Length: 106 amino acids
Theoretical weight: 11.51 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
RM20E1 Fab Heavy Chain Chain: F
Molecule details ›
Chain: F
Length: 123 amino acids
Theoretical weight: 13.88 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens
RM20E1 Fab Kappa Chain Chain: N
Molecule details ›
Chain: N
Length: 112 amino acids
Theoretical weight: 12.37 KDa
Source organism: Macaca mulatta
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.42Å
Relevant EMDB volumes: EMD-21232
Expression system: Homo sapiens