X-ray diffraction
2Å resolution

Crystal structure of ancestral apicomplexan lactate dehydrogenase with sulfate and NADH4.

Source organism: Apicomplexa sp.
Entry authors: Theobald DL, Wirth JD, Classen S, Perlmutter N

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
lactate dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 330 amino acids
Theoretical weight: 35.91 KDa
Source organism: Apicomplexa sp.
Expression system: Escherichia coli BL21

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 12.3.1
Spacegroup: P3121
Unit cell:
a: 84.695Å b: 84.695Å c: 196.007Å
α: 90° β: 90° γ: 120°
R R work R free
0.251 0.25 0.262
Expression system: Escherichia coli BL21