› › Structure analysis

Structure of ALDH7A1 mutant R441C complexed with NAD

X-ray diffraction
2.02Å resolution
PDB entry 6v0z coloured by chain, front view.
PDB entry 6v0z coloured by chain, side view.
PDB entry 6v0z coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Alpha-aminoadipic semialdehyde dehydrogenase
hide full assembly name
Multimeric state: homo tetramer
Accessible surface area: 59894.77 Å2
Buried surface area: 26622.41 Å2
Dissociation area: 9,263.35 Å2
Dissociation energy (ΔGdiss): 116.91 kcal/mol
Dissociation entropy (TΔSdiss): 17.93 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-155949
Assembly 2
Download    3D Visualisation
Assembly Name: Alpha-aminoadipic semialdehyde dehydrogenase
hide full assembly name
Multimeric state: homo tetramer
Accessible surface area: 60334.97 Å2
Buried surface area: 26223.58 Å2
Dissociation area: 3,553.06 Å2
Dissociation energy (ΔGdiss): 41.33 kcal/mol
Dissociation entropy (TΔSdiss): 16.49 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-155949

Macromolecules

Alpha-aminoadipic semialdehyde dehydrogenase
Chains: A, B, C, D, E, F, G, H
Length: 513 amino acids
Theoretical weight: 55.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P49419 (Residues: 29-539; Coverage: 95%)
Gene names: ALDH7A1, ATQ1
Pfam: Aldehyde dehydrogenase family
InterPro:
Alpha-aminoadipic semialdehyde dehydrogenase in PDB entry 6v0z, assembly 1, front view.
Alpha-aminoadipic semialdehyde dehydrogenase in PDB entry 6v0z, assembly 1, side view.
Alpha-aminoadipic semialdehyde dehydrogenase in PDB entry 6v0z, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links