X-ray diffraction
2.1Å resolution

Structure of serine hydroxymethyltransferase 8 from Glycine max cultivar Forrest complexed with PLP


Function and Biology Details

Reaction catalysed:
5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Serine hydroxymethyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 473 amino acids
Theoretical weight: 52.39 KDa
Source organism: Glycine max
Expression system: Escherichia coli
  • Canonical: A0A0R0IK90 (Residues: 71-541; Coverage: 87%)
Gene names: 100305380, GLYMA_08G108900
Sequence domains: Serine hydroxymethyltransferase

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Unit cell:
a: 56.12Å b: 127.97Å c: 128.03Å
α: 90° β: 90° γ: 90°
R R work R free
0.184 0.181 0.225
Expression system: Escherichia coli