› 6ukz

X-ray diffraction
1.52Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171337 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Stimulator of interferon genes protein; Ubiquitin-like protein SMT3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 300 amino acids
Theoretical weight: 34.46 KDa
Source organisms: Expression system: Escherichia coli
UniProt:
  • Canonical: Q12306 (Residues: 2-98; Coverage: 96%)
  • Canonical: Q86WV6 (Residues: 155-341; Coverage: 49%)
Gene names: D9719.15, ERIS, MITA, SMT3, STING, STING1, TMEM173, YDR510W
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand QBG 1 x QBG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 36.44Å b: 109.13Å c: 59.03Å
α: 90° β: 95.41° γ: 90°
R-values:
R R work R free
0.199 0.198 0.213
Expression system: Escherichia coli

Quick links

Citations

61 review citations

Combination strategies with PD-1/PD-L1 blockade: current advances and future directions.
Yi et al. (2022)
60 more

2 mentions without citation

The Many Ways to Deal with STING.
Coderch et al. (2023)
1 more