Assemblies
Assembly Name:
Protease and DNA
Multimeric state:
hetero tetramer
Accessible surface area:
46934.43 Å2
Buried surface area:
13491.63 Å2
Dissociation area:
2,526
Å2
Dissociation energy (ΔGdiss):
12.57
kcal/mol
Dissociation entropy (TΔSdiss):
13.19
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-120702
Macromolecules
Chain: A
Length: 572 amino acids
Theoretical weight: 65.89 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli
UniProt:
Pfam:
Length: 572 amino acids
Theoretical weight: 65.89 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli
UniProt:
- Canonical:
P04585 (Residues: 588-1147; Coverage: 39%)
Pfam:
- Reverse transcriptase (RNA-dependent DNA polymerase)
- Reverse transcriptase thumb domain
- Reverse transcriptase connection domain
- RNase H
Chain: B
Length: 440 amino acids
Theoretical weight: 51.38 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli
UniProt:
Pfam:
Length: 440 amino acids
Theoretical weight: 51.38 KDa
Source organism: HIV-1 M:B_HXB2R
Expression system: Escherichia coli
UniProt:
- Canonical: P04585 (Residues: 588-1027; Coverage: 31%)
Pfam:
- Reverse transcriptase (RNA-dependent DNA polymerase)
- Reverse transcriptase thumb domain
- Reverse transcriptase connection domain
Name:
DNA primer
Representative chains: P
Length: 21 nucleotides
Theoretical weight: 6.36 KDa
Representative chains: P
Length: 21 nucleotides
Theoretical weight: 6.36 KDa
Name:
DNA template
Representative chains: T
Length: 27 nucleotides
Theoretical weight: 8.45 KDa
Representative chains: T
Length: 27 nucleotides
Theoretical weight: 8.45 KDa
