› 6u9p

X-ray diffraction
1.65Å resolution

Wild-type MthK pore in ~150 mM K+

Released:
DOI: 10.2210/pdb6u9p/pdb
PDB 6u9p coloured by chain and viewed from the front.
PDB 6u9p coloured by chain and viewed from the side.
PDB 6u9p coloured by chain and viewed from the top.
Source organism: Methanothermobacter thermautotrophicus
Primary publication:
Selectivity filter ion binding affinity determines inactivation in a potassium channel.
Boiteux C, Posson DJ, Allen TW, Nimigean CM
Proc Natl Acad Sci U S A 117 29968-29978 (2020)
PMID: 33154158

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium-gated potassium channel MthK Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 8.98 KDa
Source organism: Methanothermobacter thermautotrophicus
Expression system: Escherichia coli
UniProt:
  • Canonical: O27564 (Residues: 18-99; Coverage: 24%)
Gene names: MTH_1520, mthK

Ligands and Environments

2 bound ligands:
Ligand K 5 x K
Ligand HEZ 1 x HEZ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P4212
Unit cell:
a: 63.811Å b: 63.811Å c: 44.05Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.183 0.208
Expression system: Escherichia coli

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