6u8d

X-ray diffraction
1.81Å resolution

Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-232193 (preferred)
Entry contents:
2 distinct polypeptide molecules
1 distinct RNA molecule
Macromolecules (3 distinct):
Heavy chain of Fab HCV2 Chain: H
Molecule details ›
Chain: H
Length: 233 amino acids
Theoretical weight: 25.02 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
Light chain of Fab HCV2 Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
JIIIabc RNA (68-MER) Chain: A
Molecule details ›
Chain: A
Length: 68 nucleotides
Theoretical weight: 22.01 KDa

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: C2
Unit cell:
a: 49.705Å b: 161.223Å c: 96.978Å
α: 90° β: 102.66° γ: 90°
R-values:
R R work R free
0.175 0.174 0.209
Expression system: Escherichia coli