Function and Biology Details
Reaction catalysed:
Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
- Aminopeptidase N-like , N-terminal domain superfamliy
- Spike glycoprotein S1, coronavirus
- ERAP1-like C-terminal domain
- Peptidase M1, membrane alanine aminopeptidase
- Peptidase M4/M1, CTD superfamily
- Aminopeptidase N-type
- Aminopeptidase N-like , N-terminal domain
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Spike glycoprotein and Aminopeptidase N (preferred)
PDBe Complex ID:
PDB-CPX-147235 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Aminopeptidase N
Molecule details ›
Spike glycoprotein
Molecule details ›
Chains: C, D
Length: 145 amino acids
Theoretical weight: 15.66 KDa
Source organism: Human coronavirus 229E
Expression system: Homo sapiens
UniProt:
Sequence domains: Coronavirus spike glycoprotein S1
Length: 145 amino acids
Theoretical weight: 15.66 KDa
Source organism: Human coronavirus 229E
Expression system: Homo sapiens
UniProt:
- Canonical:
Q1HVL8 (Residues: 292-432; Coverage: 12%)
Sequence domains: Coronavirus spike glycoprotein S1
