6tav

X-ray diffraction
4.2Å resolution

Crystal structure of endopeptidase-induced alpha2-macroglobulin

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Alpha-2-macroglobulin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 1474 amino acids
Theoretical weight: 163.47 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P01023 (Residues: 1-1474; Coverage: 100%)
Gene names: A2M, CPAMD5, FWP007
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P212121
Unit cell:
a: 130.8Å b: 260.3Å c: 281.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.235 0.282
Expression system: Homo sapiens