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A model of the EIAV CA-SP hexamer (C6) from Gag-deltaMA spheres assembled at pH6

Electron Microscopy
3.7Å resolution
PDB entry 6t64 coloured by chain, front view.
PDB entry 6t64 coloured by chain, side view.
PDB entry 6t64 coloured by chain, top view.
Source organism: Equine infectious anemia virus
Assembly composition:
homo octadecamer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Gag polyprotein
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Multimeric state: homo octadecamer
Accessible surface area: 197273.71 Å2
Buried surface area: 47338.79 Å2
Dissociation area: 23,669.4 Å2
Dissociation energy (ΔGdiss): 59.98 kcal/mol
Dissociation entropy (TΔSdiss): 242.91 kcal/mol
Symmetry number: 6
PDBe Complex ID: PDB-CPX-159646

Macromolecules

Gag polyprotein
Chains: A, B, C
Length: 486 amino acids
Theoretical weight: 54.88 KDa
Source organism: Equine infectious anemia virus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P69730 (Residues: 1-486; Coverage: 100%)
Gene name: gag
Pfam:
InterPro:
Gag polyprotein in PDB entry 6t64, assembly 1, front view.
Gag polyprotein in PDB entry 6t64, assembly 1, side view.
Gag polyprotein in PDB entry 6t64, assembly 1, top view.
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