X-ray diffraction
1.2Å resolution

Affimer9 co-crystalised with the CH domains of alpha actinin 2.


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-actinin-2 Chain: A
Molecule details ›
Chain: A
Length: 254 amino acids
Theoretical weight: 29.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P35609 (Residues: 19-270; Coverage: 28%)
Gene name: ACTN2
Sequence domains: Calponin homology (CH) domain
Affimer 9 Chain: B
Molecule details ›
Chain: B
Length: 91 amino acids
Theoretical weight: 10.9 KDa
Source organism: synthetic construct
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P212121
Unit cell:
a: 46.192Å b: 48.519Å c: 146.993Å
α: 90° β: 90° γ: 90°
R R work R free
0.15 0.149 0.164
Expression system: Escherichia coli