6stf

X-ray diffraction
2.4Å resolution

Function and Biology Details

Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-8A Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 178 amino acids
Theoretical weight: 20.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61006 (Residues: 5-176; Coverage: 83%)
Gene names: MEL, RAB8, RAB8A
Sequence domains: Ras family

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 117.55Å b: 75.18Å c: 107.7Å
α: 90° β: 100.48° γ: 90°
R-values:
R R work R free
0.234 0.233 0.262
Expression system: Escherichia coli BL21(DE3)