› 6slr

X-ray diffraction
2.38Å resolution

Structure of saposin B in complex with atovaquone

Released:
DOI: 10.2210/pdb6slr/pdb
PDB entry 6slr coloured by chain, front view.
PDB entry 6slr coloured by chain, side view.
PDB entry 6slr coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zubieta C, Milliken B, Doyle R

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139657 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Saposin-B Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 81 amino acids
Theoretical weight: 8.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07602 (Residues: 195-272; Coverage: 15%)
Gene names: GLBA, PSAP, SAP1
Sequence domains: Saposin-like type B, region 2

Ligands and Environments

2 bound ligands:
Ligand GOL 3 x GOL
Ligand AOQ 2 x AOQ
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P3221
Unit cell:
a: 75.707Å b: 75.707Å c: 95.475Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.233 0.278
Expression system: Escherichia coli

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