› 6sjx

Solution NMR

Precursor structure of the self-processing module of iron-regulated FrpC of N. Meningitidis with calcium ions

Released:
DOI: 10.2210/pdb6sjx/pdb
PDB entry 6sjx coloured by chain, ensemble of 14 models, front view.
PDB entry 6sjx coloured by chain, ensemble of 14 models, side view.
PDB entry 6sjx coloured by chain, ensemble of 14 models, top view.
Source organism: Neisseria meningitidis serogroup C
Primary publication:
Structural Basis of Ca2+-Dependent Self-Processing Activity of Repeat-in-Toxin Proteins.
Kuban V, Macek P, Hritz J, Nechvatalova K, Nedbalcova K, Faldyna M, Sebo P, Zidek L, Bumba L
mBio 11 (2020)
PMID: 32184239

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157203 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Iron-regulated protein FrpC Chain: A
Molecule details ›
Chain: A
Length: 182 amino acids
Theoretical weight: 19.25 KDa
Source organism: Neisseria meningitidis serogroup C
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: P55127 (Residues: 416-591; Coverage: 10%)
Gene name: frpC

Ligands and Environments

1 bound ligand:
Ligand CA 5 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: simulated annealing
Expression system: Escherichia coli K-12

Quick links

Citations

2 citation in other articles

JMM Profile: Actinobacillus pleuropneumoniae: a major cause of lung disease in pigs but difficult to control and eradicate.
Stringer et al. (2022)
1 more

2 mentions without citation

Phylogenetic Analysis of Filifactor alocis Strains Isolated from Several Oral Infections Identified a Novel RTX Toxin, FtxA.
Oscarsson et al. (2020)
1 more