X-ray diffraction
4.5Å resolution

Pseudo-atomic crystal structure of the desmoglein 2 - human adenovirus serotype 3 fibre knob complex


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fiber protein Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 21.27 KDa
Source organism: Human adenovirus B3
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P04501 (Residues: 129-319; Coverage: 60%)
Gene name: L5
Sequence domains: Adenoviral fibre protein (knob domain)
Desmoglein-2 Chain: D
Molecule details ›
Chain: D
Length: 238 amino acids
Theoretical weight: 26.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q14126 (Residues: 149-386; Coverage: 22%)
Gene names: CDHF5, DSG2
Sequence domains: Cadherin domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: I213
Unit cell:
a: 146.53Å b: 146.53Å c: 146.53Å
α: 90° β: 90° γ: 90°
R R work R free
0.367 0.367 0.37
Expression system: Escherichia coli BL21(DE3)