PDB 6s7o structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

Dolichyl diphosphooligosaccharide + [protein]-L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine

Biochemical function:

protein binding

Biological process:

protein N-linked glycosylation

Cellular component:

membrane

Sequence domains:

2 more domains

Structure analysis Details

Assembly composition:

hetero octamer (preferred)

PDBe Complex ID:

PDB-CPX-138207 (preferred)

Entry contents:

8 distinct polypeptide molecules

Macromolecules (11 distinct):

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A Chain: A

Molecule details ›

Chain: A
Length: 705 amino acids
Theoretical weight: 80.61 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P46977 (Residues: 1-705; Coverage: 100%)

Gene names: ITM1, STT3A, TMC
Sequence domains:

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 Chain: B

Molecule details ›

Chain: B
Length: 37 amino acids
Theoretical weight: 4.2 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P0C6T2 (Residues: 1-37; Coverage: 100%)

Gene name: OST4
Sequence domains: Oligosaccaryltransferase

Transmembrane protein 258 Chain: C

Molecule details ›

Chain: C
Length: 79 amino acids
Theoretical weight: 9.08 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P61165 (Residues: 1-79; Coverage: 100%)

Gene names: C11orf10, HSPC005, TMEM258
Sequence domains: Oligosaccharyltransferase subunit 5

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 Chain: D

Molecule details ›

Chain: D
Length: 113 amino acids
Theoretical weight: 12.5 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P61803 (Residues: 1-113; Coverage: 100%)

Gene name: DAD1
Sequence domains: DAD family

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 Chain: E

Molecule details ›

Chain: E
Length: 607 amino acids
Theoretical weight: 68.66 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P04843 (Residues: 1-607; Coverage: 100%)

Gene name: RPN1
Sequence domains: Ribophorin I

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 Chain: F

Molecule details ›

Chain: F
Length: 631 amino acids
Theoretical weight: 69.35 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P04844 (Residues: 1-631; Coverage: 100%)

Gene name: RPN2
Sequence domains: Oligosaccharyltransferase subunit Ribophorin II

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Chain: G

Molecule details ›

Chain: G
Length: 456 amino acids
Theoretical weight: 50.75 KDa
Source organism: Homo sapiens
UniProt:

Canonical: P39656 (Residues: 1-456; Coverage: 100%)

Gene names: DDOST, KIAA0115, OK/SW-cl.45, OST48
Sequence domains: Oligosaccharyltransferase 48 kDa subunit beta

Oligosaccharyltransferase complex subunit OSTC Chain: H

Molecule details ›

Chain: H
Length: 149 amino acids
Theoretical weight: 16.84 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt: