6s22

X-ray diffraction
1.96Å resolution

Crystal structure of the TgGalNAc-T3 in complex with UDP, manganese and FGF23c

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Polypeptide N-acetylgalactosaminyltransferase Chain: A
Molecule details ›
Chain: A
Length: 631 amino acids
Theoretical weight: 72.37 KDa
Source organism: Taeniopygia guttata
Expression system: Komagataella pastoris
UniProt:
  • Canonical: H0ZAB5 (Residues: 1-631; Coverage: 100%)
Gene name: GALNT3
Sequence domains:
Fibroblast growth factor 23 C-terminal peptide Chain: F
Molecule details ›
Chain: F
Length: 12 amino acids
Theoretical weight: 1.41 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9GZV9 (Residues: 170-181; Coverage: 5%)
Gene names: FGF23, HYPF, UNQ3027/PRO9828

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P212121
Unit cell:
a: 50.957Å b: 104.823Å c: 143.466Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.216
Expression systems:
  • Komagataella pastoris
  • Not provided